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Serotonin synthesis was increased

Its mechanism of action is similar to that of non-steroidal anti-inflammatory drugs (NSAIDs)

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As BU is mainly metabolized by glutathione S-transferase (GST), we investigated the relationship between GSTA1, GSTM1 and GSTP1 genotypes with first-dose BU PKs, and the relationship with HSCT outcomes in 69 children receiving myeloablative conditioning regimen

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