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Accordingly, our pimonidazole staining suggest that both the lung tissues and dLNs of the Mtb -infected C57BL/6 mice exhibited a hypoxic state, compared with that in uninfected mice or mice exposed to 95% O 2

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Pharmacological inhibition of nNOS protected hepatocytes in culture against APAP-induced cell death44, and mice deficient in nNOS showed less liver injury after an APAP overdose41

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paragallinarum also contains other oxidative stress-related genes, such as catalase ( katA ), superoxide dismutase ( sodA ), and peroxidase ( prx ), which may complement the role of GR [37,38,39]