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CNA was applied on the conformational ensemble of the s Lif:LipA complex generated from the above MD simulations, constituting the ground state (see Materials and Methods section for details)

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Further Reading Buchner A, Merrell PW, Carpenter WM

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Many studies have demonstrated an enhanced reliance on mitochondrial oxphos following the stress of therapeutic exposure in various cancer types

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Importantly, the perturbations of C22 GlcCer biosynthesis via the knockdown of elo-3 , sptl-1 , or cgt-3 disrupted the membrane expression of CHC-1::GFP, which was restored upon C22 ceramide supplementation (Fig