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What Recent 5Amino1MQ Data Shows Enzymatic Inhibition: 5-Amino-1MQ is a small molecule inhibitor of Nicotinamide N-methyltransferase (NNMT), an enzyme often overexpressed in the adipose tissue of subjects with metabolic dysfunction

5-Amino-1MQ and Muscle Function The effects of NNMT inhibition in muscle tissue mirror those observed in adipose tissue, with increased GLUT4 expression and greater energy turnover

5-Amino-1MQ is a novel NNMT inhibitor that works at the epigenetic level to regulate cellular energy pathways

2022, doi: 10.1016/j.cmet.2022.07.013

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