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NRF2 is a master regulator of antioxidant response as a transcription factor regulating expression of several enzymes responsible for glutathione synthesis, including glutamate-cysteine ligase modifier subunit (GCLM) and the glutamate-cysteine catalytic subunit (GCLC), as well as enzymes related to GSH utilization, such as glutathione reductase, glutathione peroxidase and glutathione S transferase (GST) [45,46]

Science (2016) 352(6292):14747

Our experiments clearly demonstrate that Immunocal pretreatment is capable of significantly reducing the degree of neurotoxicity observed with aluminum in CGN cultures

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Yates J.R., Sepp T., Matharu B.K., Khan J.C., Thurlby D.A., Shahid H., Clayton D.G., Hayward C., Morgan J., Wright A.F., et al

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