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Thus, NADPH availability is a critical determinant of GSH-dependent defense against ferroptosis 4

Consistently, DMF significantly induced the expression of antioxidant proteins such as Nqo1 and Gpx4, which are critical for detoxification reaction and GSH utilization (Fig

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doi: 10.3389/fimmu.2021.749659

For each transcript, the table reports the log 2 -transformed average gProcessed signal from three biological replicates, the fold change between the various experimental groups expressed as log 2 ratio (LPS vs control and BSO/LPS vs LPS) and the respective P -value for each comparison, obtained by two-tailed Students t -test

Despite limited effects on offspring mice, PCs continue to show potential as a treatment for GDM, but their long-term safety and mechanisms require further research and verification