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160 Mechanistically, Cu can increase the production of ROS, which are intrinsically linked to malignant cell transformation

doi: 10.1016/j.redox.2024.103077

Individuals who are deficient in vitamin B12 may also consider B12 injections

The dominant driver is reduced caloric intake

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Reference intervals for serum MMA based on the overall sample are available and also on a subpopulation with serum B12 values said to be indicative of B12 repletion (i.e., 300pmol/L) and normal renal function based on serum creatinine (See Table 22b.8)