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A WHO consultation identified the most vulnerable groups as elderly individuals, infants, preschool-aged children, and pregnant or lactating women, due to either increased nutritional demands or impaired absorption capacity ( Addressing the prevention of B12 deficiency and its public health implications requires a comprehensive, life-course approach based on integrated strategies targeting early detection, dietary optimisation, and effective supplementation, in order to mitigate the long-term consequences of inadequate cobalamin status (Organization, 2000)

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(184) put forward that -cell autoimmunity correlates with reduced abundance of butyrate- and lactate-producing bacteria

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"Orthobiologics" is a term for regenerative agents that can accelerate healing and recovery from injuries and can help avoid surgery, instead healing the root cause of the problem more naturally and more completely