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Nasca C, Rasgon N, McEwen B (2019) An emerging epigenetic framework of systemic and central mechanisms underlying stress-related disorders

May JM, Harrison FE

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While this study demonstrates that CPT-1 is dispensable for macrophage polarization to M2 and highlights the importance of CoA availability, future research using genetic approaches should shed more light on the importance of FAO in M2 polarization ( Another distinctive feature of IL4-treated macrophages is the up-regulation of CD36 by PPAR, a signaling receptor and FA transporter that participates in macrophage alternative activation (73)