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In C57BL/6J mice, TMAO significantly decreased the expression of ABCG5/G8 (69)

Interestingly, this process is dependent on a low concentration of chloride (Naito and Ueda, 1985)

Translated into score terms: the IIEF-5 score in these patients improved from a baseline median of 7 (severe ED rarely able to achieve erection sufficient for intercourse) to 17 (mild ED usually able to complete intercourse) at 6 months
But remember, as urologists, we see a lot of delicate conditions, and are here to help

Acta neuropathologica Commun (2021) 9(1):199
