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doi:10.1007/s00345-023-04512-x

34 EndicottS

This molecule is an antibiotic and presents an anticancer activity by inhibiting DNA synthesis

The majority of clinical investigations conducted thus far are characterized by limited sample sizes, abbreviated intervention periods, and diverse study designs, thereby complicating the establishment of optimal dosing regimens, timing of administration, and the effective combinations of these therapeutic modalities

loss of MAVS associated protective, antiviral interferon production, activation of the NF-K pathway, inflammasommes, and innate immunity with hyper-inflammatory state and cytokine storm

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