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This unique property means both local and systemic administration can support healing, though local injection near the injury typically produces faster results

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However, the exact nature of the embryonic progenitors that give rise to adult tissue-resident macrophages, and the mechanisms enabling macrophage population maintenance in adults are still not well studied

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The plurality of intracellular proteins is degraded by the ubiquitin (Ub)proteasome pathway (UPP)