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Missing several doses in a row may require restarting at a lower dose to avoid reintroducing GI side effects

The longest trials run 24 years and show a favorable safety profile with sustained weight loss and cardiovascular benefits

it offers complementary benefits to aid in weight management

It is possible, as the authors imply, that there might be some other anti-inflammatory benefits that are having an outcome on cancer risk reduction. Wolff-Sagy shared that future work would involve looking at other cohort studies, expanding the demographics and timeframe of the study, and digging into the molecular mechanisms behind GLP-1 treatments

The safety considerations for any peptide or medication involve weighing benefits against risks for each individual patient

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