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qRT-PCR analysis of SASP markers and MARS1 in HCMECs treated for 24h with K-Hcy-modified or unmodified recombinant HMGB1/2 (1 g/mL) ( n = 3)

Oral formulations typically demonstrate greater room temperature stability and longer shelf life, though refrigeration extends potency for any peptide product

PLoS ONE 7 , e45518 (2012)

It reduces brain lipid peroxidation (LPO) and protein carbonyl levels [139]

Transcriptomic analysis also provided deep insight into the modulation of genes involved in cell wall reinforcement, reactive oxygen species (ROS) production, and programmed cell death (Akbar et al

38,39 Cryocrystallography improved X-ray resolution by reducing radiation damage through cryogenic cooling