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A study conducted by the National Library of Medicine shows that: The main component of cigarette smoke is nicotine

Overall tobacco use is higher among US residents who live in rural areas and in the Midwest, those with lower levels of household income and educational attainment, those who are uninsured or insured by Medicaid, those experiencing psychological distress, and those who have a disability (49)(184)

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Vogt F, Hall S, Marteau TM: General practitioners and family physicians negative beliefs and attitudes towards discussing smoking cessation with patients: a systematic review