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Epub 2021 Aug 10

1 2 "Tobacco History"

Smoking carcinogens act directly on cancer cells and their precursors to stimulate proliferation and inhibit apoptosis

With respect to chemical constituents present in the aerosol of heated tobacco products which are not listed on the 2012 US FDA HPHC list, the significant majority of studies have indicated that levels of numerous chemical constituents such as free radicals (Shein and Jeschke, 2019

Cowie GA, Swift E, Borland R, Chaloupka FJ, and Fong GT
The focus stays simple and consistent
