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Assessing the lung cancer risk reduction potential of cMRTPs is hampered by (i) the absence of clinical risk markers that are predictive of future lung cancer development, (ii) the latency of lung cancer manifestation (decades of smoking), and (iii) the slow reduction in excess risk upon cessation and a fortiori upon switching to a cMRTP
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Evidence suggests that e-cigarettes may be safer than regular cigarettes The biggest danger from tobacco is the smoke, and e-cigarettes dont burn

They were named after the very town where Reynolds built his first factory