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10.1021/jf5009204 26 YunJ.Cheng-TuoN.Zhen-MingL.Xiao-JuanZ.Li-JuanC.Jin-SongS.et al (2020)

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The tobacco ingredients used for making snus have been pasteurized or heated briefly at high temperatures, making sure any bacteria that can produce cancer-causing chemicals are eliminated

As for whether an increase in e-cigarette use has perhaps led to a decrease in use of other tobacco products, Krech said that WHO could not at this time say whether that has an impact or not. However, he acknowledged that many tobacco smokers are so-called dual-users using both combustible cigarettes and e-cigarettes

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Because take-up rates are so low, and there is robust evidence they increase the probability of smoking cessation in RCTs, increasing the use of medications like varenicline could be a cost-effective intervention