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Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase

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In 1927, the American Tobacco Company began a campaign for Lucky Strike by claiming that 11,105 physicians endorsed Luckies as less irritating to sensitive or tender throats than any other cigarettes. (This number almost doubled in later ads to 20,679 Physicians.) Doubtless, similar methods were used to collect the data. Doctors did not sit idly by and allow their profession to be commandeered by big tobacco