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In a recent study of people who had smoked nearly five joints a day, five days a week, for more than a decade, researchers saw that heavy pot smokers had weaker responses to the stimulant methylphenidate, which is used to treat attention-deficit/hyperactivity disorder, than nonusers

Do this by soaking a small area for a few minutes in water and your chosen detergent and then blotting with a paper towel to see if any dye transfers

And honestly

Immunoblotting Briefly, muscle samples were homogenized in lysis buffer, supplemented with a protease inhibitor cocktail [10 M sodium fluoride and 1 mM phenylmethylsulphonyl fluoride (PMSF)] (Santa Cruz Biotech, Santa Cruz, CA)

Researchers observed significant differences in disease progression between the two groups

For most people, not in a meaningful or lasting way, which is why it is suggested to quit vaping