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Table 1 Clinical trials involving iron-chelators in Alzheimers disease (AD) and Parkinsons disease (PD)

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Further purification of this 55 kDa band was accomplished by ion-exchange column chromatography using DEAE-sepharose with a 150-450 mM NaCl gradient

Peroxisome proliferator-activated receptor gamma (PPAR) agonists inhibit Th17-cell production by eliminating GLS1, reducing the levels of the downstream metabolite of -KG, 2-HG, and downregulating the levels of the activating histone marker of H3K4 methylation (H3K4me3) in the promoter and CNS2 regions of the IL-17 gene ( Figure 2 ) (51, 52)

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Canonne-Hergaux, F