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Chen, J., Kelley, W

BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial-mesenchymal transition

Med (United States)

Taheri F, Ochoa JB, Faghiri Z, Culotta K, Park HJ, Lan MS, et al

Its job is simple to describe, even if the biology sounds technical

The replacement of protons by deuterium nuclei at a specific position inside the molecule has two effects: (i) a signal decrease in the QELT spectra for the corresponding chemical group itself and (ii) a change in the structure of multiplets due to change in scalar coupling, which can potentially induce changes in signal intensity, phase, line width, and chemical shift of the spectral pattern of the different coupling partners