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For functional enrichment analysis, the R package gprofiler2 (v.0.2.0) was used to identify enriched functional terms (GO:MF, GO:BP, GO:CC, KEGG pathways and REACTOME pathways)

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EMBO Rep (2006) 7(9):8805.10.1038/sj.embor.7400779 117 BertolottiAWangXNovoaIJungreisRSchlessingerKChoJHet alIncreased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice