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Results Data were collected from 257 929 participants (unweighted).26 Of these, 51 063 (19.8%) participants smoked cigarettes: 20 487 (40.1%) predominantly smoked RYO cigarettes and 29 188 (57.2%) predominantly smoked FM cigarettes (unweighted, 1388 with missing data on the type of cigarette predominantly smoked)

Clinical Pharmacology and Therapeutics

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2) It should not be exposed to extreme temperatures for prolonged periods

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For new products to receive marketing approval for a new product, a manufacturer would need to demonstrate that the new product would be appropriate for the protection of the public health, taking into account both the likelihood of new tobacco product initiation and the increased or decreased likelihood that existing users of current tobacco products would stop using such products