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An assay measuring the abundance of H2AX in human bronchial epithelial cells can, therefore, be used to evaluate whether the extent of DNA double-strand breaks caused by the cMRTP aerosol is lower than that caused by cigarette smoke [47, 48]

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In support of this possibility, the study found that fewer participants in the gradual quit group managed to actually quit on their predetermined quit day, as compared with the abrupt quit group
E-cigarette aerosol contains chemicals such as formaldehyde, acrolein, and heavy metals, all of which are linked to cancer

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