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According to Truveta Research presented at ISPOR 2025, side effects were the leading reason patients stopped taking GLP-1 medications, accounting for 28.2% of all discontinuations

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Slowed gastric emptying, hypoglycemia (especially for diabetics), pancreatitis risk amplification, dehydration, and worsened GI side effects make alcohol on Ozempic harder to tolerate

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Nutritional monitoring becomes particularly important during aggressive weight loss phases, though this should be assessed on an individual basis
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