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Most recently, as chronicled in Patrick Radden Keefes book, Empire of Pain, a top FDA official who led the approval of Purdue Pharmas opioid OxyContin then left the agency for the company and a $400,000 compensation package

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A comparison of smoking behaviours between patients treated with clozapine and depot neuroleptics

The difference is that nicotine is highly addictive and creates dependence by disrupting the brain's normal neurotransmitter balance over time

The agency warns that highly concentrated product use can lead to tolerance, and these products likely should not be used more than once per week