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[155] Concerns have been raised that non-combustible nicotine products could lead adolescents and young adults to start smoking cigarettes later on

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A week ago, the Food and Drug Administration (FDA) approved the marketing of electronic nicotine delivery systems (ENDS) made by Glas, a Los Angeles company that specializes in devices that incorporate age verification technology

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Additionally, it has been reported that nicotine metabolism is impaired and even reduced by tobacco smoke through the inhibition of CYP2A6, which is mainly responsible for the conversion to cotinine (Lee et al., 1987

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