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Introduction# MET-097i and semaglutide both target the GLP-1 receptor for obesity treatment but represent different generations of the technology

It is also worth noting that our comparison with topiramate, which shares a weight loss property, may partly reflect topiramates poor real-world tolerability and compliance rather than a true pharmacological advantage of GLP1 RAs. However, he also stated that the overall signal is encouraging and justifies further investigation

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Clinical data from the STEP trials show that weight loss on semaglutide 2.4mg begins to plateau meaningfully around 24 months, at which point most achievable weight loss has been realized

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This dual action effectively lowers food intake and assists with blood sugar control
