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Purpose To develop a whole-heart fibrosis imaging and deep learning (DL)-based quantification method and validate the workflow by assessing the efficacy of a glucagon-like peptide-1 receptor (GLP-1R) agonist in mouse HFpEF model

We evaluated the effects of metformin, administered at different intervals before an intraduodenal glucose infusion, on the subsequent glycaemic, insulinaemic and GLP-1 responses in metformin-treated type 2 diabetes

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