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They found that MASH-related histologic changes and noninvasive test responses (including histologic resolution of MASH without worsening of liver fibrosis, ALT responses, and FibroScan AST [FAST] responses), as well as fibrosis-related histologic improvement and noninvasive test responses (including improvement in fibrosis without worsening of MASH, VCTE responses, and ELF score responses), were greater in patients receiving semaglutide than in patients receiving placebo, even at a similar amount of weight reduction

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Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity

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A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes (PIONEER 12)
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