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[1] [2] These combined effects improve glycaemic control in people with type 2 diabetes

That overlap is exactly what the 72-hour rule is designed to prevent
Comparative efficacy of pharmacologic therapies for MASH in reducing liver fat content: systematic review and network meta-analysis

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For Study 4, the primary efficacy parameter was mean percent change in body weight from randomization (Week 36) to Week 88

Daily activities that previously felt easy start requiring more relative effort