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The advanced stage of this is called metabolic dysfunction-associated steatohepatitis, or MASH, which is the leading cause of liver-rated medical conditions and mortality
Gastrointestinal discomfort and nausea are the most common side effects, but those related to patients physical appearance often receive the most attention

By May 2025, GLP-1s accounted for 52% of all diabetes prescription volume, up from just 18% in 2020

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