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If you are losing 1 to 2 pounds per week consistently, there may be no reason to increase

It's the mechanism tirzepatide was designed to deliver, and it does so more consistently than any weight loss intervention that preceded it
Vision changes: If you notice any sudden changes in your vision while taking tirzepatide, get immediate medical attention

A cystatin C-based eGFR provides accurate kidney function assessment regardless of creatine use

For anyone with arrhythmia history or existing cardiac conditions, this is a meaningful concern that requires direct conversation with a prescriber
