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Among those who did not adhere to their initial treatment within the 1year followup period, 90.5% of metformin initiators and 94.2% of GLP1RA initiators did not start another glucoselowering therapy afterward

139141 Although dual agonists show advantages in efficacy, their safety and tolerability continue to be a focus of ongoing monitoring

Tirzepatide While semaglutide works on a single hormone, tirzepatidethe active ingredient in brand-name drugs Mounjaro and Zepboundis a dual-hormone medication, according to Anekwe

Results highlighted that liraglutide induced significant weight loss but did not reduce knee pain compared to placebo [48]

Wegovy Showed the Strongest Signal Although Ozempic generated far more reports overall because it was approved earlier, Wegovy showed the strongest association with ION