perioperative management of glp-1 agonists Anesthetic Considerations for Patients Taking Glucagon-Like Peptide-1 π¬π§ Perioperative Management of New
Description
Tirzepatide is the agonist of GLP-1 receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor, which can reduce body weight and improve cardiac metabolism by subcutaneous injection once a week (Jastreboff et al 2022)
Cloning the GLP-1 receptor Another important chapter was opened up for understanding the biology of GLP-1 by the cloning of the GLP-1 receptor

Cignas announcement to phase out rebates in favor of upfront discounts is an important signal that the system needs change

Given the positive effects that GLP1 receptor agonists have on weight, significant interest exists in better understanding their potential role in managing osteoarthritis and associated pain

Importantly, this decision applied only to the obesity indication ( 7 , 8 )

In patients with T2DM and hepatic steatosis, Cuthbertson et al