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Some complaints cite clinical trials and post-marketing safety data as part of the argument that drug makers knew or should have known about serious motility risks, while defendants dispute both causation and the interpretation of the evidence

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It appears to reduce insulin resistance, helping cells respond better to insulin
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Individuals who are pregnant, planning on becoming pregnant, breastfeeding, have a history of severe kidney or liver disease, pancreatitis, gallbladder disease, diabetic retinopathy, thyroid C-cell tumors, certain types of cancer, or those who have had severe hypersensitivity to Semaglutide or any of its components may not be suitable for this treatment

J Neurosci 31(17):65876594 Hansen HH, Barkholt P, Fabricius K, Jelsing J, Terwel D, Pyke C, Knudsen LB, Vrang N (2016) The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy
