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These agents demonstrated superior glycemic efficacy compared with many earlier therapies and offered clinically meaningful weight reduction, establishing a new standard of care for patients with type 2 diabetes and obesity

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Current medical guidelines recommend stopping GLP-1 medications three months before attempting conception due to limited pregnancy safety data

Additionally, it is clear that tirzeaptide induces less nausea per nmol in circulation compared to the GLP-1R monoagonists despite the improvement in weight loss