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G49, a dual glucagon/glucagon-like peptide-1 receptor agonist, triggers an inter-organ crosstalk between adipose tissue, pancreas and liver, leading to brown fat activation with the final outcomes of increased energy expenditure and body weight loss.

Exec SummaryDanuglipron is an experimental weight loss medication being developed by Pfizer

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GLP-1 agonists may lessen alcohol, smoking and possibly drug addictions

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