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Ongoing #GLP1 -RA Trials on #ASCVD #SELECT: Semaglutide vs Placebo in Patients With Obesity and ASCVD Without DM #SOUL: Semaglutide vs Placebo in Adults With T2D With ASCVD or CKD #SURPASS-CVOT: Tirzepatide vs Dulaglutide in Patients With T2D and ASCVD #SURMOUNT-MMO:

Because GCGR activation is associated with changes in hepatic energy metabolism and lipid oxidation pathways, GLP-RTprovides a framework for studying how multiple endocrine signaling inputs influence whole-body energy partitioning in controlled experimental environments [5]

Semaglutide injections can be administered regardless of meal timing, but clinical evidence suggests fasting may optimize absorption and GI tolerability

Methods In this open-label, single-center, casecontrol pilot study, patients with IIH (pwIIH) and a body mass index (BMI) of30 kg/m2 were offered to receive a GLP-1-RA (semaglutide, liraglutide) in addition to the usual care weight management (UCWM)

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