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Many experience increased hunger, the return of "food noise," changes in blood sugar control and the loss of some cardiometabolic benefits, while side effects like nausea and constipation often improve

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A diferencia que otros medicamentos utilizados en el manejo de diabetes, y al igual que los inhibidores SGLT2 (iSGLT2), es poca la evidencia sobre asociacin de este grupo farmacolgico con sintomatologa gastrointestinal42