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Despite the ongoing legal battle that GLP-1 agonists have, they are widely used and prescribed even with the side effects they can cause

However, many primary care clinicians hesitate to initiate basal insulin due to concerns regarding time or effort needed to educate patients, doubts about patient acceptance or ability to manage titration or injection, or patient fears of hypoglycemia
Overall, this combination stabilizes mood, restores brainpower, and keeps the mind clear and focused

How this indication expansion will impact the ability for generic manufacturing of sema I am unsure, but my assumption is that generic sem and GLP-1s will be available long before resmetirom

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