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Regular exercise increases metabolic rate, generates body heat, and helps preserve lean muscle mass during weight loss

The safety and efficacy of this specific combination have not been directly evaluated by the FDA

Topical treatments : For localized joint pain, particularly in osteoarthritis, topical NSAIDs such as diclofenac gel can provide relief with fewer systemic side effects than oral medications

Side Effects: Both drugs share similar side effects, including nausea, vomiting, and gastrointestinal discomfort, but these are generally mild and decrease over time as the body adjusts to the medication

At minimum: complete metabolic panel, thyroid panel (TSH, free T3, free T4), fasting insulin, HbA1c, cortisol, and a lipid panel