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Semaglutide may not be suitable for everyone, particularly those who are pregnant or breastfeeding, have a history of pancreatitis, or have an allergy to the medication

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For diuretic nave patients, furosemide 40 mg IV is a reasonable starting dose For patients already on diuretics prior to admission, increasing their home dose by 2.5x (administered intravenously) usually achieves an adequate initial response Patients should be reassessed 1-2 hours after their initial diuretics dose
Sleep: the overlooked reset amplifier Poor sleep actively works against GLP-1 receptor sensitivity

Microdoses hover around 1.5 mg and very often even lower

Advise patients to report new-onset psoriasis symptoms to their healthcare provider
