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In the published Phase 2 obesity trial (Jastreboff et al., NEJM 2023), doses of up to 12 mg once weekly were studied

Side effect tolerance Temporary digestive symptoms can occur as the body adjusts to treatment
There were 97 exclusions after browsing the title, including 79 review articles or meta-analyses, and another 18 studies were excluded because their subjects were unrelated

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Figure 10.Change from Baseline (%) in BMI in Pediatric Patients with Obesity Aged 12 Years and Older in Study 7 Observed values for patients completing each scheduled visit, and estimates with multiple imputations from retrieved dropouts (RD-MI) Figure 11.Change in BMI (%) from Baseline to Week 68 in Pediatric Patients with Obesity Aged 12 Years and Older in Study 7 Observed data from in-trial period including imputed data for missing observations (RD-MI) Effect of WEGOVY on Anthropometry and Cardiometabolic Parameters in Pediatric Patients with Obesity Aged 12 Years and Older Changes in waist circumference and cardiometabolic parameters with WEGOVY are shown in Table 14 for the study in pediatric patients aged 12 years and older
